Weight Loss Neurotransmitters & Brain Chemistry

© Peter Smith –Holistic Medicine Practitioner-
(VERSION# 28/2/13)

Unfortunately manipulating your neurotransmitters to either help you lose weight or suppress your appetite is only really of any help to people who actually have a deficiency of neurotransmitters in the first place giving rise to either depression, bipolar syndrome or anxiety.  
If you have normal brain chemistry and you don't have any of these conditions I'm sorry to tell you but manipulating your brain chemistry is unlikely to help you in the battle of the bulge.  I really wish there was some magic secret dieting formula I could share with you that would reliably suppress appetite and stop overeating. Just like giving serotonin reuptake inhibiting antidepressants to a person who doesn't have depression or a deficiency in serotonin it's probably not have any effect at all.  On the other hand if you're overweight because your response to depression or bipolar syndrome or anxiety is to overbeat then using the methods on this website to balance your brain chemistry and stabilise those conditions or reduce those conditions will probably help you to lose weight.  Also if you have mental health problems and the medication you've taken such as antidepressants or lithium has caused you to gain weight then using the methods on this website may enable you to give up those medications and manage your condition with alternative therapies which do not cause weight gain will also help you lose weight.
Over the years I’ve tried to utilise my understanding of how to change neurotransmitter levels with natural remedies to create a weight loss effect, sadly the results were largely disappointing in anyone that didn't have depression, bipolar syndrome or anxiety. My thinking was that if you could increase the body's production of the chemical cholecystokinin CCK that tells us when we are full by supplementing L-phenylalanine you’d be able to suppress appetite but it did not produce noticeable results. There has been a couple of scientific studies on the ability of L-phenylalanine to raise CCK and although the results were impressive with a as much as a 30% reduction in calorie consumption the effects were not really practical applications. Firstly you had to take a whopping 10,000 mg and secondly you had to time the dose quite precisely to be effective. For more practical ways of reducing your appetite see:  Weight-Loss Method 1:How to Naturally Suppress Your Appetite & Feel Fuller with Fewer Calories. 
Another approach I’ve tried is increasing the neurotransmitter dopamine to control addictive food cravings because of its connection to drug addiction but the jury is still out on any benefits. 
Sorry to disappoint you but on this website I'm trying to only recommend techniques I know actually work, so if you don't have a mental health problem manipulating your neurotransmitters or brain chemistry is probably not going to help you lose weight you can still use all the other methods for weigh loss on this site.  If on the other hand you do have a weight problem and you feel sure that it's connected to your a mental health problem either because of overheat or the side effects of conventional meds then you may achieve a lot of weight loss by using the methods on this website and in my book to balance your brain chemistry to treat those conditions.  
In contrast to many conventional mental health meds none of the medications that I use for balancing brain chemistry cause weight gain.
Under construction and fellow Basten or thing Larling to treat addictive food eating/depression.
[UNDER CONSTRUCTION] (add phenylalanine/tyrosine for genuine sugar addiction.


  1. Appetite control techniques, How to Feel Fuller with Fewer Calories.
  2. Eliminate surplus glucose supply and stabilize blood sugar. To store fat easily the body needs surplus glucose, eliminate this and you make it harder for the body to become fat. Stabilising blood sugar also reduces food craving. 
  3. Balance brain chemistry to conquer food cravings/addictions.
  4. Eliminate excess levels of the stress hormone cortisol (if present). Excess cortisol can cause the body to accumulate body fat, especially abdominal fat. 
  5. Increase the body’s overall metabolic rate by growing muscle mass.
Be Well
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What I Treat

I treat and coach people with mental health problems at my London clinic and via Skype how to use natural remedies, diet, brain training meditations, sleep and specific physical exercises to treat the health of the brain for mental health problems including:
  • bipolar syndrome,
  • depression,
  • anxiety,
  • addiction, panic disorder OCD and PTSD
I teach meditation brain training classes both  one-to-one and in small groups to rewire the brain and treat mental health problems.  I also see clints for cognitive hypnotherapy and NLP amygdala reprogramming or exposure therapy to treat anxiety spectrum disorders.
I regret that at this time do not treat psychotic conditions including schizophrenia at this time. 

I Specialise in the treatment of digestive health problems:
  • IBS (irritable bowel syndrome)
  • SIBO  (which can be the cause of  60% of IBS)
  • Bloating, constipation etc.
To book an appointment for the above conditions at my London clinic call my clinic reception ,
tobook a Skype appointment do not call my clinic  email me directly

For Costs and Fees click here
To make an appointment at my London clinic (not for Skype appointments) call my reception:
020 7631 0156
To make a Skype appointment do not call my clinic, email me 


Mobile phone 07941 331 329
My other site: underdevelopment
 © PeterSmithUK.com –Holistic Medicine Consultant-
For a more information on my practice and a list of conditions I treat click here About My Practice 
Over the years I’ve trained in Nutritional /naturopathic medicine, Cognitive Hypnotherapy and NLP, body-centred psychotherapy, Chinese herbal medicine, Acupuncture, Bicom resonance therapy, meditation and Kundalini yoga, in the past I specialised in digestive health problems including IBS, bloating, candida, parasites, constipation, Heavy metal detoxification and chronic fatigue syndrome including adrenal exhaustion. I practice at the Hale Clinic (central London) and via Skype as a holistic medical practitioner and have been in practice since 1988.
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